SCHEMBL13613400

SCHEMBL13613400

CCCN1C(=O)NC2(CC(C)(C)N(C)C(C)(C)C2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
CNR1 P21554 3/20 0.36
POLB P06746 2/20 0.35
ALDH1A1 P00352 4/20 0.34
CYP19A1 P11511 2/20 0.34
KMT2A Q03164 1/20 0.34
TACR1 P25103 1/20 0.34
PLA2G7 Q13093 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11155430 0.90 CNR1 (0.47) LMNACNR1ALDH1A1CYP19A1TACR1
SCHEMBL11091144 0.88 CNR1 (0.49) CNR1ALDH1A1CYP19A1TACR1
SCHEMBL11482548 0.87 ALDH1A1 (0.43) LMNACNR1ALDH1A1TACR1
SCHEMBL11484787 0.86 POLB (0.50) LMNAPOLBALDH1A1KMT2ARAB9A
SCHEMBL11478679 0.84 ALDH1A1 (0.47) LMNAALDH1A1PLA2G7
SCHEMBL11475914 0.83 ALDH1A1 (0.39) LMNAPOLBALDH1A1KMT2APLA2G7
SCHEMBL11476879 0.81 ALDH1A1 (0.33) LMNAPOLBALDH1A1KMT2APLA2G7
SCHEMBL11484696 0.81 ALDH1A1 (0.51) LMNAALDH1A1KMT2ARAB9A
SCHEMBL11477918 0.80 POLB (0.59) LMNACNR1POLBALDH1A1CYP19A1
SCHEMBL11484847 0.80 LMNA (0.48) LMNAPOLBALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090312464-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-12-17 US disclosed
US-7332105-B2 Synergistic UV absorber combination CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-19 US disclosed
US-7169835-B2 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-30 US disclosed