Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.46 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891121 | 0.78 | KDM4E (0.45) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL18635889 | 0.77 | MPO (0.55) | CHRM2BCHEACHELMNASMN1; SMN2 | |
| SCHEMBL8850869 | 0.73 | HDAC3 (0.58) | CHRM2BCHEACHELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL28493003 | 0.72 | HDAC3 (0.56) | CHRM2BCHEACHELMNAALDH1A1 | |
| SCHEMBL24018766 | 0.69 | IFNAR1 (0.51) | CHRM2LMNAALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL19438874 | 0.69 | HDAC3 (0.65) | CHRM2LMNAALDH1A1 | |
| SCHEMBL28467893 | 0.69 | CA12 (0.60) | — | |
| SCHEMBL3014350 | 0.69 | NPC1 (0.53) | CHRM2ALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL16730575 | 0.68 | HDAC3 (0.66) | CHRM2BCHEACHELMNAALDH1A1 | |
| SCHEMBL13903744 | 0.68 | HDAC3 (0.66) | CHRM2BCHEACHELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |