SCHEMBL9891121

SCHEMBL9891121

COC(=O)Cc1ccccc1SC(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MMP2 P08253 3/20 0.39
MMP9 P14780 3/20 0.39
MMP12 P39900 3/20 0.39
MMP14 P50281 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 2/20 0.39
EGFR P00533 3/20 0.38
SLC7A5 Q01650 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CFD P00746 1/20 0.38
CETP P11597 1/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504829 0.86 TSHR (0.54) POLBHSD17B10L3MBTL1MMP2MMP9
SCHEMBL9430367 0.81 LMNA (0.51) KDM4EPOLBHSD17B10L3MBTL1MMP2
SCHEMBL4060152 0.80 KDM4E (0.42) KDM4EPOLBHSD17B10L3MBTL1MMP2
SCHEMBL18504820 0.79 SMN1; SMN2 (0.47) KDM4EPOLBMMP2MMP9MMP12
SCHEMBL1554320 0.78 KDM4E (0.53) KDM4EPOLBHSD17B10L3MBTL1SMN1; SMN2
SCHEMBL13613425 0.78 CHRM2 (0.46) SMN1; SMN2TSHRALDH1A1
SCHEMBL10175060 0.76 PTGS2 (0.51) KDM4EPOLBHSD17B10L3MBTL1MMP2
SCHEMBL4309048 0.75 KDM4E (0.48) KDM4EPOLBHSD17B10L3MBTL1SMN1; SMN2
SCHEMBL21423238 0.75 ACHE (0.38) POLBL3MBTL1CETPGFER
SCHEMBL19688866 0.75 GABRA1 (0.46) KDM4EPOLBHSD17B10L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367282-B2 Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production FUJIFILM CORPORATION (JP) 2013-02-05 US disclosed
US-20120238752-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120154944-A1 COLOR CURABLE COMPOSITION AND METHOD OF PREPARING THE SAME, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE PICK-UP DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-8197994-B2 Colorant of a dipyrromethene-based metal complex obtained from a metal of iron, zinc, cobalt, copper or vanadium oxide and a dipyrromethene-based compound and a phthalocyanine dye FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-20120138877-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110234950-A1 COLOR FILTER AND ELECTRONIC DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-09-29 US disclosed
US-20110217636-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-09-08 US disclosed
WO-2011027846-A1 COLOR CURABLE COMPOSITION AND METHOD OF PREPARING THE SAME, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE PICK-UP DEVICE FUJIFILM CORPORATION (JP) 2011-03-10 WO disclosed
US-20100230647-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION FUJIFILM CORPORATION (JP) 2010-09-16 US disclosed
US-20080076044-A1 Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238752-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION PBRM1, CRY1, MAPT KDM4E 296/4885POLB 1574/4885HSD17B10 3764/4885
US-20100230647-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION CRY1, IK, PRMT5 KDM4E 493/4885POLB 2408/4885HSD17B10 4277/4885
US-20080076044-A1 Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production PBRM1, CRY1, MAPT KDM4E 296/4885POLB 1574/4885HSD17B10 3764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.