SCHEMBL13613765

SCHEMBL13613765

CC(C)C[C@@H](C(=O)OC(C)(C)C)N(CCC(=O)CNC(=O)OC(C)(C)C)C(=O)CNC(=O)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.46
CTSK P43235 4/20 0.42
CTSS P25774 3/20 0.42
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
HSD17B10 Q99714 1/20 0.41
POLB P06746 2/20 0.40
GAA P10253 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4350950 0.94 SYK (0.46) SYKCTSKCTSSCTSLCTSB
SCHEMBL13613734 0.86 SYK (0.44) SYKCTSKCTSSCTSLCTSB
SCHEMBL12880713 0.86 SYK (0.48) SYKCTSKCTSSCTSLCTSB
SCHEMBL16318175 0.82 CAPN1 (0.46) SYKCTSKCTSSCTSLCTSB
SCHEMBL4348014 0.82 CTSS (0.46) SYKCTSKCTSSCTSLCTSB
SCHEMBL4348011 0.82 CTSS (0.46) SYKCTSKCTSSCTSLCTSB
SCHEMBL4343782 0.81 CTSL (0.34) CTSKCTSSCTSLCTSBPOLB
SCHEMBL12880631 0.80 PSEN1 (0.42) SYKCTSKCTSSCTSLCTSB
SCHEMBL7907133 0.78 SYK (0.62) SYKCTSKCTSSCTSLCTSB
SCHEMBL4343773 0.76 CTSK (0.48) SYKCTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275727-A1 Peptide turn mimetics MIMETICA PTY LIMITED (AU) 2009-11-05 US disclosed
US-20090275727-A1 Peptide turn mimetics MIMETICA PTY LIMITED (AU) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275727-A1 Peptide turn mimetics IAPP, GLP1R, VIP SYK 3770/4885CTSK 1231/4885CTSS 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.