Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | SNCA | P37840 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614049 | 0.83 | ASIC3 (0.49) | MAPTSMN1; SMN2ALDH1A1APP | |
| SCHEMBL13614046 | 0.80 | KCNH2 (0.47) | LMNAHTTSMN1; SMN2APPBCHE | |
| SCHEMBL13614031 | 0.78 | MAPT (0.53) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL15112995 | 0.72 | ALDH1A1 (0.48) | MAPTHTTNPSR1ALDH1A1APP | |
| SCHEMBL10300053 | 0.72 | ALDH1A1 (0.65) | MAPTALDH1A1APPSNCAADK | |
| SCHEMBL770159 | 0.72 | ALDH1A1 (0.65) | MAPTALDH1A1APPSNCAADK | |
| SCHEMBL17170384 | 0.70 | APP (0.40) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL13486851 | 0.70 | APP (0.48) | MAPTMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL13486852 | 0.70 | UGT2B7 (0.49) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL26913789 | 0.68 | NPC1 (0.48) | MAPTALDH1A1APPSNCANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611546-B2 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-20090064423-A1 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090064423-A1 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | KRT18, HADHB, KAT7 | MAPT 1412/4885MEN1 2508/4885LMNA 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.