Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268991 | 0.80 | APP (0.52) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL12277733 | 0.78 | APP (0.52) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL12269201 | 0.78 | APP (0.50) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL13561726 | 0.77 | ALDH1A1 (0.48) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL12277638 | 0.74 | APP (0.54) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL12260007 | 0.74 | APP (0.54) | APPTERTNSD2MAPTTHRB | |
| SCHEMBL12278361 | 0.74 | APP (0.47) | APPTERTNSD2NPSR1ALDH1A1 | |
| SCHEMBL13569393 | 0.70 | APP (0.51) | APPTERTMEN1KMT2ALMNA | |
| SCHEMBL13614047 | 0.70 | MAPT (0.41) | APPMAPTTHRBNPSR1SMN1; SMN2 | |
| SCHEMBL12566471 | 0.70 | TERT (0.64) | APPTERTNSD2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702870-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160313312-A1 | Fluorescent Dyes and Related Methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2016-10-27 | — | — | US | disclosed |
| US-9410947-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-9410947-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150293080-A1 | Fluorescent Dyes and Related Methods | NATIONAL SCIENCE FOUNDATION | 2015-10-15 | — | — | US | disclosed |
| US-20150293080-A1 | Fluorescent Dyes and Related Methods | NATIONAL SCIENCE FOUNDATION | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160313312-A1 | Fluorescent Dyes and Related Methods | HNRNPH3, CDC73, EWSR1 | APP 3789/4885TERT 473/4885NSD2 2044/4885 |
| US-20150293080-A1 | Fluorescent Dyes and Related Methods | CDC73, DDB1, HNRNPH3 | APP 3909/4885TERT 593/4885NSD2 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.