Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804623 | 0.82 | GABRA1 (0.38) | CYP4F2CYP4A11AKR1C3LTB4RLTB4R2 | |
| SCHEMBL12152309 | 0.82 | GABRA1 (0.38) | CYP4F2CYP4A11AKR1C3LTB4RLTB4R2 | |
| SCHEMBL25383248 | 0.82 | MAOA (0.48) | ALDH1A1CYP4F2CYP4A11LTB4RLTB4R2 | |
| SCHEMBL5036742 | 0.81 | TP53 (0.46) | OPRM1OPRD1OPRK1ALDH1A1CYP1A2 | |
| SCHEMBL17103311 | 0.81 | MAOA (0.42) | OPRM1OPRD1OPRK1ALDH1A1CYP1A2 | |
| SCHEMBL30189129 | 0.80 | CYP4F2 (0.41) | OPRM1OPRD1OPRK1CYP4F2CYP4A11 | |
| SCHEMBL28699652 | 0.80 | CYP4F2 (0.41) | OPRM1OPRD1OPRK1CYP4F2CYP4A11 | |
| SCHEMBL9579004 | 0.79 | OPRM1 (0.50) | OPRM1OPRD1OPRK1TAAR1AOC3 | |
| SCHEMBL8434164 | 0.77 | CYP4F2 (0.39) | CYP4F2CYP4A11LTB4RLTB4R2CNR2 | |
| SCHEMBL25382740 | 0.76 | ESR1 (0.48) | OPRM1OPRD1OPRK1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629343-B2 | Carbamic acid compounds comprising a piperazine linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2009-12-08 | — | — | US | disclosed |