Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064473 | 0.84 | HRH1 (0.38) | TAAR1CA2MAPTNPSR1HTR2A | |
| SCHEMBL11001435 | 0.81 | LTA4H (0.37) | CA2MAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL692925 | 0.75 | LTA4H (0.37) | CA2MAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL11695994 | 0.75 | HPGD (0.36) | MAPT | |
| SCHEMBL28943133 | 0.74 | CYP2D6 (0.39) | TAAR1CA2MAPTNPSR1HTR2A | |
| SCHEMBL30515258 | 0.73 | HTR2A (0.44) | TAAR1MAPTNPSR1HTR2ALMNA | |
| SCHEMBL6159693 | 0.71 | P2RX4 (0.36) | MAPTNPSR1LMNASMN1; SMN2LTA4H | |
| SCHEMBL3928537 | 0.71 | P2RX4 (0.36) | MAPTNPSR1LMNASMN1; SMN2LTA4H | |
| SCHEMBL8038103 | 0.71 | AOC2 (0.43) | MAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL13752382 | 0.67 | CA2 (0.43) | TAAR1CA2MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973540-B1 | USE OF BENZO-FUSED HETEROCYCLE SULFAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009120189-A1 | USE OF BENZO-FUSED HETEROCYCLE SULFAMIDE DERIVATIVES FOR THE TREATMENT OF ANXIETY | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-10-01 | — | — | WO | disclosed |