Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761305 | 0.91 | CYP3A4 (0.41) | CYP3A4CYP2C9APPPDK2ACMSD | |
| SCHEMBL11891678 | 0.90 | CYP3A4 (0.52) | CYP3A4CYP2C9APPPDK2S1PR1 | |
| SCHEMBL18385875 | 0.89 | CYP3A4 (0.50) | CYP3A4CYP2C9APPPDK2S1PR1 | |
| SCHEMBL18392484 | 0.87 | CYP3A4 (0.36) | CYP3A4CYP2C9APPPDK2S1PR1 | |
| SCHEMBL9501457 | 0.86 | CYP3A4 (0.60) | CYP3A4CYP2C9APPPDK2ACMSD | |
| SCHEMBL18411541 | 0.85 | CYP3A4 (0.50) | CYP3A4CYP2C9APPPDK2ACMSD | |
| SCHEMBL19097887 | 0.84 | CYP3A4 (0.38) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL91870 | 0.84 | FASN (0.43) | CYP3A4CYP2C9APPPDK2CYP2D6 | |
| SCHEMBL20083445 | 0.84 | KDM1A (0.38) | CYP3A4CYP2C9APPPDK2CYP2D6 | |
| SCHEMBL21525831 | 0.84 | CYP3A4 (0.49) | CYP3A4CYP2C9APPPDK2ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-11739267-B2 | LC medium | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11667840-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230056437-A1 | AZO DYE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| US-11359142-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2022-06-14 | — | — | US | disclosed |
| US-11352560-B2 | Liquid crystal mixture and liquid crystal display | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-9737854-B2 | Process for the purification of a liquid-crystal mixture | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| EP-2806010-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2017-07-26 | — | — | EP | disclosed |
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9657231-B2 | Liquid crystal medium and high-frequency components containing the same | MERCK PATENT GMBH (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20170137713-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| EP-2818533-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT EMPLOYING SAME | DAINIPPON INK & CHEMICALS (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-9650573-B2 | Liquid crystalline medium and liquid crystal device | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9611428-B2 | Liquid-crystalline medium and electro-optical liquid-crystal display | MERCK PATENT GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20170037315-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | US | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | CYP3A4 1706/4885CYP2C9 1963/4885APP 161/4885 |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | CYP3A4 1991/4885CYP2C9 1308/4885APP 624/4885 |
| US-11667840-B2 | Liquid-crystalline medium | FES, BLM, CXCL12 | CYP3A4 4420/4885CYP2C9 4206/4885APP 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.