SCHEMBL13614776

SCHEMBL13614776

Fc1cc(-c2ccccc2)ccc1-c1cc(F)c(F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.43
FEN1 P39748 1/20 0.43
DHODH Q02127 3/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
APAF1 O14727 1/20 0.42
NPC1 O15118 1/20 0.42
THRB P10828 1/20 0.42
XBP1 P17861 1/20 0.42
PTBP1 P26599 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
GALK1 P51570 1/20 0.42
BLM P54132 1/20 0.42
SMAD3 P84022 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18231889 1.00 ALOX5AP (0.43) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL28566500 0.89 PTGS1 (0.49) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL2140807 0.89 PTGS1 (0.49) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL15077185 0.89 PTGS1 (0.49) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL19308531 0.87 FEN1 (0.50) ALOX5APFEN1MEN1KMT2ALMNA
SCHEMBL17108386 0.87 ESR1 (0.41) ALOX5APFEN1MEN1KMT2ALMNA
SCHEMBL20663902 0.87 MEN1 (0.48) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL19400433 0.87 MEN1 (0.50) ALOX5APFEN1MEN1KMT2ALMNA
SCHEMBL19502507 0.86 DHODH (0.45) ALOX5APFEN1DHODHMEN1KMT2A
SCHEMBL20310666 0.85 ESR2 (0.46) ALOX5APFEN1DHODHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20230313043-A1 OPTICAL COMPONENT MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-03-02 US disclosed
US-20230056437-A1 AZO DYE MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20230053362-A1 DICHROIC DYE COMPOSITION MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20220220383-A1 METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2022-07-14 US disclosed
WO-2022129018-A1 HETEROAROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
US-9726933-B2 Liquid-crystal displays and liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2017-08-08 US disclosed
EP-2806010-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2017-07-26 EP disclosed
EP-3179303-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-06-14 EP disclosed
US-20170137713-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
EP-2818533-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT EMPLOYING SAME DAINIPPON INK & CHEMICALS (JP) 2017-05-17 EP disclosed
US-20170096602-A1 LIQUID CRYSTAL COMPOSITION HAVING EASILY ADJUSTABLE ROTATIONAL VISCOSITY DONGJIN SEMICHEM CO., LTD. (KR) 2017-04-06 US disclosed
US-20170037315-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 US disclosed
US-20170037316-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 US disclosed
US-20170029702-A1 LIQUID CRYSTAL MATERIAL MERCK PATENT GMBH (DE) 2017-02-02 US disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037316-A1 LIQUID-CRYSTALLINE MEDIUM FES, NEFM, SOST ALOX5AP 4672/4885FEN1 2673/4885DHODH 4742/4885
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY CXCR1, PYM1, F11 ALOX5AP 2205/4885FEN1 4220/4885DHODH 4401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.