SCHEMBL2140807

SCHEMBL2140807

Fc1cc(-c2ccccc2)ccc1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
PTGS2 P35354 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
FABP2 P12104 1/20 0.49
TSHR P16473 1/20 0.49
AKR1C4 P17516 1/20 0.49
ADRA2B P18089 1/20 0.49
CHRM3 P20309 1/20 0.49
HTR2C P28335 1/20 0.49
DRD3 P35462 1/20 0.49
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
AKR1C1 Q04828 1/20 0.49
SLC22A6 Q4U2R8 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15077185 1.00 PTGS1 (0.49) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL28566500 1.00 PTGS1 (0.49) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL19308531 0.98 FEN1 (0.50) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL19400433 0.98 MEN1 (0.50) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL19308543 0.94 PTPRC (0.52) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL18716177 0.94 CYP2C9 (0.47) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL20663902 0.93 MEN1 (0.48) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL10091190 0.90 MAPT (0.49) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL19493701 0.90 PTGS1 (0.42) PTGS1MEN1KMT2APTGS2LMNA
SCHEMBL19393955 0.90 TAAR1 (0.58) PTGS1MEN1KMT2APTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT TOSOH CORPORATION (JP) 2024-07-25 US disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
US-20240072425-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-11834599-B2 Aromatic isothiocyanates MERCK PATENT GMBH (DE) 2023-12-05 US disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-4273148-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4261269-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2023-10-18 EP disclosed
EP-3670503-B1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING SAME, AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD (CN) 2023-10-18 EP disclosed
US-11739265-B2 Aromatic isothiocyanates MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
US-11739266-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
CN-1138819-C Bis (trialkyl trimellitic anhydride) derivatives and polyesterimides for optical communications 三星电子株式会社 2004-02-18 CN disclosed
US-20030162950-A1 Coupling catalyst and process using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2003-08-28 US disclosed
CN-1425660-A Di (trialkylbenzotri acid anhydride) devivative for optic communication SAMSUNG ELECTRONICS CO LTD (KR) 2003-06-25 CN disclosed
EP-1306131-A2 Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-05-02 EP disclosed
CN-1226572-A Bis (trialkyl trimellitic anhydride) derivatives and polyesterimides for optical communications SAMSUNG ELECTRONICS CO LTD (KR) 1999-08-25 CN disclosed
CN-1225359-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO LTD (KR) 1999-08-11 CN disclosed
EP-0132377-B1 COMPOUNDS CONTAINING A FLUOROBIPHENYLYL GROUP AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICE The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-06-29 EP disclosed
US-4696549-A Compounds containing a fluorobiphenylyl group and their use in liquid crystal material and devices THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1987-09-29 US disclosed
US-4594465-A Compounds containing a fluorobiphenylyl group THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1986-06-10 US disclosed
EP-0132377-A2 Compounds containing a fluorobiphenylyl group and their use in liquid crystal materials and device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162950-A1 Coupling catalyst and process using the same NOD1, PYM1, C9 PTGS1 1035/4885MEN1 279/4885KMT2A 1134/4885
US-20240072425-A1 AROMATIC ISOTHIOCYANATES TRPA1, TRPC1, CRY1 PTGS1 4117/4885MEN1 580/4885KMT2A 903/4885
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT AXIN2, FZD7, SLC39A3 PTGS1 1856/4885MEN1 1023/4885KMT2A 2097/4885
US-11739265-B2 Aromatic isothiocyanates TRPA1, CRY1, FOXM1 PTGS1 3827/4885MEN1 585/4885KMT2A 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.