Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12565683 | 0.89 | MEN1 (0.39) | CNR1ALDH1A1NAAADNM1MEN1 | |
| SCHEMBL4578116 | 0.83 | MEN1 (0.37) | ALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL8956908 | 0.82 | MEN1 (0.37) | DNM1MEN1KMT2A | |
| SCHEMBL4578248 | 0.81 | ALDH1A1 (0.41) | CNR1ALDH1A1NAAAMEN1KMT2A | |
| SCHEMBL5034969 | 0.80 | MCL1 (0.41) | ALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL1569983 | 0.80 | DNM1 (0.40) | CNR1ALDH1A1NAAADNM1MEN1 | |
| SCHEMBL9547143 | 0.79 | DNM1 (0.34) | CNR1ALDH1A1NAAADNM1MEN1 | |
| Hydrochloric Acid SCHEMBL7583332 | 0.78 | DNM1 (0.39) | CNR1ALDH1A1NAAADNM1MEN1 | |
| SCHEMBL25381115 | 0.76 | CNR1 (0.38) | CNR1ALDH1A1NAAAMEN1KMT2A | |
| SCHEMBL26838432 | 0.76 | MCL1 (0.48) | CNR1NAAADNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |