Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068827 | 0.84 | MEN1 (0.37) | MEN1KMT2ARAB9ADNM1HDAC1 | |
| SCHEMBL8956453 | 0.83 | HDAC1 (0.40) | MEN1KMT2ARAB9ADNM1HDAC1 | |
| SCHEMBL4578116 | 0.82 | MEN1 (0.37) | MEN1KMT2ARAB9ADNM1SMN1; SMN2 | |
| SCHEMBL8956368 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2ARAB9ADNM1HDAC1 | |
| SCHEMBL13614831 | 0.82 | CNR1 (0.40) | MEN1KMT2ADNM1 | |
| SCHEMBL5034969 | 0.79 | MCL1 (0.41) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL24393605 | 0.77 | DNM1 (0.35) | MEN1KMT2ADNM1HDAC1HDAC10 | |
| SCHEMBL26838432 | 0.74 | MCL1 (0.48) | MEN1KMT2ARAB9ADNM1SMN1; SMN2 | |
| SCHEMBL582964 | 0.73 | ALDH1A1 (0.31) | MEN1KMT2A | |
| SCHEMBL888282 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |