SCHEMBL13629264

SCHEMBL13629264

COc1cc(/N=N/c2c(S(=O)(=O)O)cc3cc(S(=O)(=O)O)c(N)cc3c2O)c(OC)cc1/N=N/c1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 8/20 0.48
PHLPP2 Q6ZVD8 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
MAPK1 P28482 2/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
PTK6 Q13882 4/20 0.39
CD40 P25942 1/20 0.39
CD40LG P29965 1/20 0.39
EGFR P00533 1/20 0.38
FYN P06241 1/20 0.38
BMX P51813 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615319 0.89 ENPP2 (0.40) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629224 0.86 SENP2 (0.46) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629245 0.84 PHLPP2 (0.55) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629753 0.83 SENP3 (0.48) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629239 0.83 ENPP2 (0.52) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL14351159 0.82 ENPP2 (0.53) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629218 0.82 ENPP2 (0.64) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629758 0.81 GLO1 (0.43) ENPP2PHLPP2MEN1KMT2AMAPT
SCHEMBL13629754 0.81 ENPP2 (0.53) ENPP2PHLPP2MEN1KMT2AALDH1A1
SCHEMBL13629223 0.81 ENPP2 (0.51) ENPP2PHLPP2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275742-A1 COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2009-11-05 US disclosed