Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862818 | 0.88 | THRB (0.40) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL19342863 | 0.88 | THRB (0.40) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL14539303 | 0.85 | THRB (0.39) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL13410112 | 0.85 | ALDH1A1 (0.44) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL13607213 | 0.85 | CYP1A1 (0.43) | SMPD1APPMAPT | |
| SCHEMBL862607 | 0.84 | AHR (0.42) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL13410111 | 0.84 | MAPT (0.45) | PTGS1PTGS2APPALOX5THRB | |
| SCHEMBL10153473 | 0.82 | THRB (0.41) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL5113975 | 0.79 | APP (0.56) | ESR1PTGS1PTGS2SMPD1APP | |
| SCHEMBL5113980 | 0.79 | APP (0.56) | ESR1PTGS1PTGS2SMPD1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615289-B2 | Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same | SK ENERGY CO., LTD. (KR) | 2009-11-10 | — | — | US | disclosed |