Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154312 | 0.88 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL3825328 | 0.87 | MEN1 (0.47) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL3825321 | 0.87 | MEN1 (0.47) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042003 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042050 | 0.86 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042043 | 0.86 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042105 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL12668082 | 0.86 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042037 | 0.86 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL15042108 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067651-B2 | 1-alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-29 | — | — | US | disclosed |
| US-20090043146-A1 | 1-Alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043146-A1 | 1-Alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | OXER1, CYP1A1, CHRM1 | L3MBTL1 3078/4885ALDH1A1 736/4885CYP2C19 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.