Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825321 | 1.00 | MEN1 (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3844849 | 0.90 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3823832 | 0.89 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3823823 | 0.89 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1361571 | 0.87 | L3MBTL1 (0.42) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3829072 | 0.86 | DGKA (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3828270 | 0.85 | ALDH1A1 (0.43) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3829040 | 0.84 | ALDH1A1 (0.42) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8154312 | 0.83 | L3MBTL1 (0.43) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3825325 | 0.83 | DGKA (0.45) | FAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |