Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615609 | 0.87 | TK1 (0.36) | — | |
| SCHEMBL16368118 | 0.84 | DUT (0.36) | DUTNT5ESMYD2P2RY14P2RY2 | |
| SCHEMBL13615887 | 0.80 | P2RY6 (0.43) | NT5ESMYD2P2RY6P2RY14P2RY2 | |
| SCHEMBL20270078 | 0.80 | P2RY2 (0.34) | DUTNT5ESLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13616344 | 0.80 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL19590312 | 0.78 | P2RY6 (0.40) | DUTNT5ESMYD2SLC28A1SLC28A2 | |
| SCHEMBL5960167 | 0.77 | P2RY14 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL5960164 | 0.77 | P2RY14 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL13721968 | 0.77 | TDP1 (0.35) | DUTNT5ESMYD2SLC28A1SLC28A2 | |
| SCHEMBL19590300 | 0.77 | NT5E (0.34) | DUTNT5ESMYD2SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |