Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 3/20 | 0.34 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616330 | 0.87 | DUT (0.36) | — | |
| SCHEMBL13615532 | 0.79 | ALDH1A1 (0.45) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL15689751 | 0.77 | TK1 (0.38) | TK1TOP2ANT5MRNASE1 | |
| SCHEMBL13273995 | 0.77 | TK1 (0.38) | TK1TOP2ANT5MALDH1A1LMNA | |
| SCHEMBL1716526 | 0.77 | TK1 (0.38) | TK1TOP2ANT5MRNASE1 | |
| SCHEMBL16478991 | 0.77 | TK1 (0.38) | TK1TOP2ANT5MALDH1A1LMNA | |
| SCHEMBL13615887 | 0.76 | P2RY6 (0.43) | ALDH1A1POLB | |
| SCHEMBL8069871 | 0.75 | TYMP (0.37) | TK1TK2NT5MALDH1A1LMNA | |
| SCHEMBL7708172 | 0.75 | TOP2A (0.41) | TK1TK2TOP2AALDH1A1LMNA | |
| SCHEMBL7708175 | 0.75 | TOP2A (0.41) | TK1TK2TOP2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |