Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316559 | 0.86 | TACR3 (0.44) | GPR139TACR3LMNAPOLBSLC6A3 | |
| SCHEMBL15443129 | 0.83 | LMNA (0.51) | TACR3LMNAPOLBTSHRMTNR1A | |
| SCHEMBL16317174 | 0.83 | LMNA (0.51) | TACR3LMNAPOLBTSHRMTNR1A | |
| SCHEMBL2628429 | 0.80 | ASAH1 (0.46) | TACR3ALDH1A1MAPT | |
| SCHEMBL25807093 | 0.79 | GPR139 (0.67) | GPR139ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13616392 | 0.79 | MEN1 (0.43) | TACR3LMNAPOLBTSHRMTNR1A | |
| SCHEMBL13050111 | 0.78 | TACR3 (0.48) | TACR3LMNAPOLBTSHRMTNR1A | |
| SCHEMBL890060 | 0.78 | TACR3 (0.48) | TACR3POLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5744468 | 0.78 | TACR3 (0.48) | TACR3POLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL18610229 | 0.78 | TACR3 (0.48) | TACR3POLBMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | CYP51A1, CYP4Z1, CYP4A11 | GPR139 1918/4885TACR3 2755/4885LMNA 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.