SCHEMBL13616453

SCHEMBL13616453

O=C(CC1CCC(CC(=O)C2CCC3OC3C2)CC1)C1CCC2OC2C1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
PMP22 Q01453 1/20 0.34
TFPI2 P48307 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
PLG P00747 1/20 0.31
PLAT P00750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14606751 0.94 LMNA (0.33) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL18651825 0.93 KDM4E (0.31) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL13630600 0.87 DPP4 (0.31)
SCHEMBL12707402 0.80 TP53 (0.35) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL14004139 0.80 PPM1B (0.37) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL18651826 0.80
SCHEMBL9187411 0.76
SCHEMBL13906805 0.74 TFPI2 (0.42) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL14830394 0.74 LMNA (0.41) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL1859238 0.74 LMNA (0.41) LMNAKDM4EGMNNPMP22TFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090281275-A1 Curable resin compositions and interlayer dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-12 US disclosed