SCHEMBL14606751

SCHEMBL14606751

O=C(CC1CCC2OC2C1)C1CCC2OC2C1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PMP22 Q01453 1/20 0.33
TFPI2 P48307 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
PLG P00747 1/20 0.31
PLAT P00750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13616453 0.94 LMNA (0.34) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL18651825 0.88 KDM4E (0.31) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL13630600 0.82 DPP4 (0.31)
SCHEMBL12707402 0.82 TP53 (0.35) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL18651826 0.81
SCHEMBL4663418 0.80 TFPI2 (0.38) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL754254 0.79 ALDH1A1 (0.43) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL14004139 0.79 PPM1B (0.37) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL11056909 0.77 TFPI2 (0.35) LMNAKDM4EGMNNPMP22TFPI2
SCHEMBL15069506 0.76 TFPI2 (0.39) LMNAKDM4EGMNNPMP22TFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850223-B2 Metal catalysts for selective formation of cyclic carbonates, process for preparing cyclic carbonate using the same and use of cyclic carbonate KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-12-26 US disclosed
US-9850223-B2 Metal catalysts for selective formation of cyclic carbonates, process for preparing cyclic carbonate using the same and use of cyclic carbonate KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-12-26 US disclosed
US-20170081302-A1 METAL CATALYSTS FOR SELECTIVE FORMATION OF CYCLIC CARBONATES, PROCESS FOR PREPARING CYCLIC CARBONATE USING THE SAME AND USE OF CYCLIC CARBONATE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-03-23 US disclosed
US-20170081302-A1 METAL CATALYSTS FOR SELECTIVE FORMATION OF CYCLIC CARBONATES, PROCESS FOR PREPARING CYCLIC CARBONATE USING THE SAME AND USE OF CYCLIC CARBONATE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-03-23 US disclosed
US-20070059478-A1 Optical recording medium and production method thereof; and optical recording apparatus and optical reproducing apparatus FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170081302-A1 METAL CATALYSTS FOR SELECTIVE FORMATION OF CYCLIC CARBONATES, PROCESS FOR PREPARING CYCLIC CARBONATE USING THE SAME AND USE OF CYCLIC CARBONATE CA2, TMCO1, CA1 LMNA 2652/4885KDM4E 1427/4885GMNN 2407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.