SCHEMBL14280396

SCHEMBL14280396

CCCCCCCCCCc1ccc2c(c1)c(=O)c1ccccc1n2C

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORA P35398 2/20 0.62
RORC P51449 2/20 0.62
RORB Q92753 2/20 0.62
ATM Q13315 2/20 0.47
OXER1 Q8TDS5 2/20 0.46
RAB9A P51151 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 3/20 0.46
PGR P06401 2/20 0.46
RXFP1 Q9HBX9 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HCRTR1 O43613 1/20 0.44
CTSV O60911 1/20 0.43
CTSL P07711 1/20 0.43
RAD52 P43351 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13616802 0.84 RORA (0.59) RORARORCRORBALDH1A1MAPT
SCHEMBL12083703 0.83 RORC (0.56) RORARORCRORBMEN1KMT2A
SCHEMBL10071739 0.83 ATM (0.54) RORARORCRORBATMRAB9A
SCHEMBL10358850 0.82 RORA (0.45) RORARORCRORBATMOXER1
SCHEMBL10358458 0.82 RORA (0.45) RORARORCRORBATMOXER1
SCHEMBL14280393 0.81 ALDH1A1 (0.53) RORARORCRORBNPC1PGR
SCHEMBL10358846 0.81 RORA (0.43) RORARORCRORBATMOXER1
SCHEMBL10358833 0.81 RORA (0.43) RORARORCRORBATMOXER1
SCHEMBL12960334 0.79 RORA (0.42) RORARORCRORBATMOXER1
SCHEMBL10358424 0.79 RORA (0.42) RORARORCRORBRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed