Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617038 | 0.92 | KDM4E (0.49) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL13617031 | 0.92 | KDM4E (0.51) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL5925710 | 0.86 | PTGS2 (0.59) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL13617041 | 0.85 | KDM4E (0.49) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL3855594 | 0.85 | KDM4E (0.53) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL3857457 | 0.84 | KMT2A (0.57) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL8252665 | 0.80 | KDM4E (0.40) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL3859674 | 0.77 | KDM4E (0.60) | KMT2AKDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL11862343 | 0.77 | CCR5 (0.55) | HPGDITGB1FPR2CA1CA2 | |
| SCHEMBL3858455 | 0.76 | KDM4E (0.59) | KMT2AKDM4EHSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | HTT, NLN, SNCA | KMT2A 717/4885KDM4E 3710/4885HSD17B10 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.