Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617041 | 0.92 | KDM4E (0.49) | CCR5PTPN1ACEITGB3GPR132 | |
| SCHEMBL10807099 | 0.90 | ACE (0.55) | PTPN1ACEITGB3GPR132ITGA2B | |
| SCHEMBL1070049 | 0.88 | GPR132 (0.52) | GPR132 | |
| SCHEMBL11859682 | 0.87 | PTPN1 (0.52) | PTPN1ACEITGB3GPR132ITGA2B | |
| SCHEMBL25471843 | 0.86 | ITGB3 (0.49) | CCR5ITGB3ITGA2BITGB1FPR2 | |
| SCHEMBL11684066 | 0.86 | ALOX15 (0.47) | CCR5CA2FPR2 | |
| SCHEMBL13617031 | 0.85 | KDM4E (0.51) | CCR5ITGB3ITGA2BITGB1HPGD | |
| SCHEMBL7814592 | 0.85 | FPR2 (0.63) | PTPN1ACEITGB3GPR132ITGA2B | |
| SCHEMBL8412092 | 0.85 | FPR2 (0.63) | PTPN1ACEITGB3GPR132ITGA2B | |
| SCHEMBL10449482 | 0.85 | FPR2 (0.63) | PTPN1ACEITGB3GPR132ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |