SCHEMBL1361743

SCHEMBL1361743

O=C(Cl)C12CC3(C(=O)Cl)CC(C(=O)Cl)(C1)CC(C(=O)Cl)(C2)C3

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143630 1.00 SMN1; SMN2 (0.31) SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL5082256 0.87 GRM1 (0.41)
SCHEMBL19357069 0.87 GRM1 (0.41)
SCHEMBL5082217 0.87 GRM1 (0.41)
SCHEMBL5081841 0.87 GRM1 (0.41)
SCHEMBL477997 0.86
SCHEMBL16941989 0.86
SCHEMBL5614130 0.83 PKM (0.54) SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL24769402 0.81
SCHEMBL23985746 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117917395-A Novel compound for light-emitting element and organic light-emitting element comprising same 东进世美肯株式会社 2024-04-23 CN disclosed
US-8067630-B1 T-butyl cascade polymers UNIVERSITY OF SOUTH FLORIDA (US) 2011-11-29 US disclosed
US-7589229-B2 Reacting nitromethane with tert-butyl acrylate to form a nitrotrialkanoate; reducing the nitrotrialkanoate to the corresponding amine monomer; amine monomer used to make spherical dendritic macromolecules based on adamantane THE UNIVERSITY OF SOUTH FLORIDA (US) 2009-09-15 US disclosed
US-7589229-B2 Reacting nitromethane with tert-butyl acrylate to form a nitrotrialkanoate; reducing the nitrotrialkanoate to the corresponding amine monomer; amine monomer used to make spherical dendritic macromolecules based on adamantane THE UNIVERSITY OF SOUTH FLORIDA (US) 2009-09-15 US disclosed
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070142663-A1 T-butyl cascade polymers THE UNIVERSITY OF SOUTH FLORIDA 2007-06-21 US disclosed
US-20070142663-A1 T-butyl cascade polymers THE UNIVERSITY OF SOUTH FLORIDA 2007-06-21 US disclosed
US-20070142663-A1 T-butyl cascade polymers THE UNIVERSITY OF SOUTH FLORIDA 2007-06-21 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7183426-B2 T-butyl cascade polymers NEWKOME GEORGE R 2007-02-27 US disclosed
US-7183426-B2 T-butyl cascade polymers NEWKOME GEORGE R 2007-02-27 US disclosed
US-20070032556-A1 Aromatic polyamine derivative DAICEL CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-08 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1681284-A1 AROMATIC POLYAMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2006-07-19 EP disclosed
US-20050101744-A1 T-butyl cascade polymers NEWKOME GEORGE R (US) 2005-05-12 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed
US-20030097019-A1 Reacting nitromethane with tert-butyl acrylate triester nitrotrialkanoate; reducing the nitrotrialkanoate to amine monomer SOUTH FLORIDA, UNIVERSITY OF 2003-05-22 US disclosed
WO-1999049831-A2 AMPLIFIED FLUORESCENT MATERIALS AND USES THEREOF MARTIN VLADIMIR V (US) 1999-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101744-A1 T-butyl cascade polymers TNK1, TST, TNNI3K SMN1; SMN2 2986/4885LMNA 2693/4885MEN1 2054/4885
US-20070032556-A1 Aromatic polyamine derivative SRM, PRMT1, KDM8 SMN1; SMN2 3372/4885LMNA 3440/4885MEN1 1236/4885
US-20030097019-A1 Reacting nitromethane with tert-butyl acrylate triester nitrotrialkanoate; reducing the nitrotrialkanoate to amine monomer TNK1, TELO2, TST SMN1; SMN2 2398/4885LMNA 3317/4885MEN1 1053/4885
US-20070142663-A1 T-butyl cascade polymers TNK1, TST, TNNI3K SMN1; SMN2 2986/4885LMNA 2693/4885MEN1 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.