⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891799 | 0.77 | PKM (0.30) | — | |
| SCHEMBL19656351 | 0.76 | — | — | |
| SCHEMBL8006729 | 0.74 | PKM (0.33) | — | |
| SCHEMBL6898990 | 0.74 | THRB (0.36) | — | |
| SCHEMBL29233420 | 0.71 | PKM (0.30) | — | |
| SCHEMBL3813974 | 0.71 | — | — | |
| SCHEMBL5916468 | 0.70 | — | — | |
| SCHEMBL2402177 | 0.70 | — | — | |
| SCHEMBL11402888 | 0.70 | — | — | |
| SCHEMBL9064012 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118056811-A | Method for preparing fluorine-containing nitrile compound by dehydrating amide compound | 浙江省化工研究院有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-118056811-A | Method for preparing fluorine-containing nitrile compound by dehydrating amide compound | 浙江省化工研究院有限公司 | 2024-05-21 | — | — | CN | disclosed |
| US-10144762-B2 | Antibacterial antisense oligonucleotide and method | SAREPTA THERAPEUTICS, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| EP-2024499-B1 | OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES | SAREPTA THERAPEUTICS INC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20170247410-A1 | ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-08-31 | — | — | US | disclosed |
| EP-2735568-B1 | Oligonucleotide analogs having cationic intersubunit linkages | AVI BIOPHARMA INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9499583-B2 | Antibacterial antisense oligonucleotide and method | SAREPTA THERAPEUTICS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160251398-A1 | ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2016-09-01 | — | — | US | disclosed |
| US-9249243-B2 | Antibacterial antisense oligonucleotide and method | SAREPTA THERAPEUTICS, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20140213737-A1 | ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | SAREPTA THERAPEUTICS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8536147-B2 | Antibacterial antisense oligonucleotide and method | SAREPTA THERAPEUTICS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8067571-B2 | Antibacterial antisense oligonucleotide and method | AVI BIOPHARMA, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-7943762-B2 | Oligonucleotide analogs having cationic intersubunit linkages | AVI BIOPHARMA, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100234281-A1 | ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2010-09-16 | — | — | US | disclosed |
| EP-2049143-A1 | IMPROVED ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | Avi Biopharma, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| US-20090088562-A1 | Oligonucleotide analogs having cationic intersubunit linkages | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2009-04-02 | — | — | US | disclosed |
| EP-2024499-A2 | OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES | Avi Biopharma, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| US-20080194463-A1 | Conjugating an arginine-rich carrier to a 3' or 5' end; phosphorodiamidate linkages | AVI BIOPHARMA, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| WO-2008036127-A2 | OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES | AVI BIOPHARMA, INC. (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2008008113-A1 | IMPROVED ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD | AVI BIOPHARMA, INC. (US) | 2008-01-17 | — | — | WO | disclosed |