Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618087 | 0.88 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838033 | 0.87 | ADRB2 (0.79) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838751 | 0.87 | ADRB2 (0.79) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838029 | 0.87 | ADRB2 (0.79) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13892808 | 0.86 | ADRB2 (0.60) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617395 | 0.85 | ADRB2 (0.79) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617678 | 0.85 | ADRB2 (0.76) | ADRB2ADRB1 | |
| SCHEMBL13617672 | 0.84 | ADRB2 (0.51) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13892875 | 0.82 | ADRB2 (0.49) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617642 | 0.82 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641465-B1 | COMBINATIONS OF AN ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONIST AND A CORTICOSTEROID | THERAVANCE INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1446379-B1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-29 | — | — | EP | disclosed |