Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617829 | 0.86 | ADRB2 (0.60) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617661 | 0.84 | ADRB2 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617395 | 0.78 | ADRB2 (0.79) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL13618087 | 0.78 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13892875 | 0.77 | ADRB2 (0.49) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13617402 | 0.77 | ADRB2 (0.66) | ADRB2ADRB1 | |
| SCHEMBL13617642 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13708435 | 0.76 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13892852 | 0.72 | MAPK1 (0.46) | ADRB2ADRB1ADRB3DRD2DRD3 | |
| SCHEMBL3838751 | 0.72 | ADRB2 (0.79) | ADRB2ADRB1ADRB3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641465-B1 | COMBINATIONS OF AN ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONIST AND A CORTICOSTEROID | THERAVANCE INC (US) | 2009-11-04 | — | — | EP | disclosed |