Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708398 | 0.86 | ADRB2 (0.57) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13617661 | 0.82 | ADRB2 (0.62) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13617642 | 0.79 | ADRB2 (0.52) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13617672 | 0.77 | ADRB2 (0.51) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13618087 | 0.77 | ADRB2 (0.69) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13617395 | 0.77 | ADRB2 (0.79) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13708392 | 0.76 | ADRB2 (0.65) | ADRB2ADRB3ADRB1 | |
| SCHEMBL13708401 | 0.76 | MAPT (0.45) | ADRB2ADRB3ADRB1MAPTKMT2A | |
| SCHEMBL13892852 | 0.71 | MAPK1 (0.46) | ADRB2ADRB3ADRB1MAPTKMT2A | |
| SCHEMBL3838751 | 0.71 | ADRB2 (0.79) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446379-B1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-29 | — | — | EP | disclosed |