Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777020 | 0.86 | EPHX2 (0.37) | CPB2 | |
| SCHEMBL29715079 | 0.85 | EPHX2 (0.39) | CPB2 | |
| SCHEMBL27756051 | 0.85 | EPHX2 (0.39) | CPB2 | |
| SCHEMBL2759042 | 0.77 | CPB2 (0.33) | CPB2 | |
| SCHEMBL3378642 | 0.75 | CPB2 (0.34) | CPB2 | |
| SCHEMBL3378638 | 0.75 | CPB2 (0.34) | CPB2 | |
| SCHEMBL669444 | 0.75 | CPB2 (0.34) | CPB2 | |
| SCHEMBL669445 | 0.75 | CPB2 (0.34) | CPB2 | |
| Hydrochloric Acid SCHEMBL30634622 | 0.75 | CPB2 (0.34) | CPB2 | |
| SCHEMBL27776882 | 0.74 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |