Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | TRHR | P34981 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 4/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756043 | 0.99 | PARP1 (0.33) | SMN1; SMN2L3MBTL1PARP1EPHX1F2 | |
| SCHEMBL27777020 | 0.88 | EPHX2 (0.37) | SMN1; SMN2L3MBTL1EPHX1EPHX2 | |
| SCHEMBL27756051 | 0.87 | EPHX2 (0.39) | SMN1; SMN2L3MBTL1EPHX1EPHX2 | |
| SCHEMBL29715079 | 0.87 | EPHX2 (0.39) | SMN1; SMN2L3MBTL1EPHX1EPHX2 | |
| SCHEMBL30179278 | 0.85 | EPHX1 (0.34) | SMN1; SMN2L3MBTL1EPHX1EPHX2 | |
| SCHEMBL11014616 | 0.81 | F2 (0.35) | PARP1F2PRSS1 | |
| SCHEMBL7397129 | 0.79 | LMNA (0.36) | SMN1; SMN2TRHR | |
| SCHEMBL18122813 | 0.79 | CPB2 (0.31) | — | |
| SCHEMBL3835496 | 0.79 | CPB2 (0.31) | — | |
| SCHEMBL13246851 | 0.79 | CPB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | claimed |
| CN-101531637-B | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GUANGZHOU INST OF BIOMEDICINE AND HEALTH | 2011-07-13 | — | — | CN | disclosed |
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |