Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669445 | 0.85 | CPB2 (0.34) | CPB2CPB1SMN1; SMN2 | |
| SCHEMBL669444 | 0.85 | CPB2 (0.34) | CPB2CPB1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30634622 | 0.85 | CPB2 (0.34) | CPB2CPB1SMN1; SMN2 | |
| SCHEMBL3378642 | 0.85 | CPB2 (0.34) | CPB2CPB1SMN1; SMN2 | |
| SCHEMBL3378638 | 0.85 | CPB2 (0.34) | CPB2CPB1SMN1; SMN2 | |
| Water SCHEMBL8430675 | 0.84 | CPB2 (0.32) | CPB2CPB1 | |
| SCHEMBL1666632 | 0.84 | CPB2 (0.36) | CPB2CPB1SMN1; SMN2 | |
| SCHEMBL4292046 | 0.84 | CPB2 (0.33) | CPB2CPB1SMN1; SMN2 | |
| SCHEMBL1073717 | 0.84 | ITGB2 (0.36) | CPB2CPB1 | |
| SCHEMBL5542778 | 0.84 | CPB2 (0.33) | CPB2CPB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | CPB2 1771/4885CPB1 1987/4885SMN1; SMN2 252/4885 |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | CPB2 1771/4885CPB1 1987/4885SMN1; SMN2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.