Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11919300 | 0.89 | TAAR1 (0.47) | TAAR1MTNR1AMTNR1BHMGCRPTGS2 | |
| SCHEMBL7720458 | 0.89 | TAAR1 (0.62) | TAAR1MTNR1AMTNR1BHMGCRCYP3A4 | |
| SCHEMBL15706606 | 0.85 | TAAR1 (0.47) | TAAR1MTNR1AMTNR1B | |
| SCHEMBL27635179 | 0.84 | MTNR1A (0.47) | TAAR1MTNR1AMTNR1BHMGCRCYP3A4 | |
| SCHEMBL24074177 | 0.84 | TAAR1 (0.47) | TAAR1CYP3A4 | |
| SCHEMBL1498704 | 0.84 | HMGCR (0.52) | TAAR1MTNR1AMTNR1BHMGCR | |
| SCHEMBL1498705 | 0.84 | HMGCR (0.47) | TAAR1MTNR1AMTNR1BHMGCRCYP3A4 | |
| SCHEMBL9954912 | 0.84 | HTR2A (0.49) | TAAR1 | |
| SCHEMBL16200094 | 0.84 | TAAR1 (0.53) | TAAR1HMGCR | |
| SCHEMBL10085676 | 0.84 | TAAR1 (0.43) | TAAR1MTNR1AMTNR1BHMGCRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133831-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | 旭化成ファーマ株式会社 (JP) | 2009-11-05 | — | — | WO | disclosed |