Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498704 | 0.92 | HMGCR (0.52) | HMGCRTAAR1MTNR1AMTNR1BTSHR | |
| SCHEMBL13618030 | 0.84 | TAAR1 (0.53) | HMGCRTAAR1MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL11919300 | 0.82 | TAAR1 (0.47) | HMGCRTAAR1MTNR1AMTNR1BMAPK1 | |
| SCHEMBL1044562 | 0.79 | MAOB (0.48) | HMGCRTAAR1TSHRMAPK1CYP1A2 | |
| SCHEMBL7723931 | 0.79 | ALOX15 (0.45) | MAPK1BACE1LMNA | |
| SCHEMBL26664827 | 0.78 | HMGCR (0.48) | HMGCRTAAR1TSHRMAPK1HSD17B2 | |
| SCHEMBL20399474 | 0.78 | HMGCR (0.48) | HMGCRTAAR1TSHRMAPK1HSD17B2 | |
| SCHEMBL28962328 | 0.78 | HSD17B2 (0.45) | HMGCRTAAR1TSHRHSD17B2CYP1A2 | |
| SCHEMBL15706606 | 0.78 | TAAR1 (0.47) | TAAR1MTNR1AMTNR1BGLA | |
| SCHEMBL9955637 | 0.78 | TAAR1 (0.41) | HMGCRTAAR1JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473480-B1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA SAS (FR) | 2016-06-01 | — | — | EP | disclosed |
| US-9272985-B2 | Antibacterial hydroxyphenyl compound | FAB PHARMA S.A.S. (FR) | 2016-03-01 | — | — | US | disclosed |
| US-20120232155-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA S.A.S. (FR) | 2012-09-13 | — | — | US | disclosed |
| EP-2473480-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB Pharma SAS (FR) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026529-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | FAB PHARMA SAS (FR) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232155-A1 | NOVEL ANTIBACTERIAL HYDROXYPHENYL COMPOUND | MRPL21, VIP, DHPS | HMGCR 288/4885TAAR1 4823/4885JAK2 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.