Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 7/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969945 | 0.81 | TAAR1 (0.48) | — | |
| SCHEMBL9860301 | 0.80 | WNT3A (0.49) | ICMTHSD17B1HSD17B2LMNAPPARG | |
| SCHEMBL8263689 | 0.78 | CTBP2 (0.49) | ICMTHSD17B1HSD17B2PPARGPPARA | |
| SCHEMBL3840860 | 0.76 | PTGS1 (0.51) | LMNADHODH | |
| SCHEMBL19512828 | 0.75 | PTGS1 (0.61) | LMNA | |
| Toluene SCHEMBL1159746 | 0.74 | L3MBTL1 (0.41) | LMNAALDH1A1 | |
| Toluene SCHEMBL8907280 | 0.74 | L3MBTL1 (0.41) | LMNAALDH1A1 | |
| Toluene SCHEMBL1079482 | 0.74 | L3MBTL1 (0.41) | LMNAALDH1A1 | |
| Toluene SCHEMBL8994440 | 0.74 | L3MBTL1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL22425266 | 0.74 | HSD17B10 (0.53) | LMNAALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |