Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146120 | 0.89 | MEN1 (0.47) | MEN1KMT2ABRD4RETEGFR | |
| SCHEMBL10147474 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL352495 | 0.73 | CNR1 (0.38) | MEN1KMT2ABRD4 | |
| SCHEMBL13618718 | 0.68 | BRD4 (0.51) | MEN1KMT2ABRD4RETEGFR | |
| SCHEMBL10147473 | 0.66 | CNR2 (0.31) | — | |
| SCHEMBL13618544 | 0.65 | MEN1 (0.45) | MEN1KMT2ABRD4RETEGFR | |
| SCHEMBL799923 | 0.61 | MEN1 (1.00) | MEN1KMT2A | |
| SCHEMBL10146122 | 0.61 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL10146103 | 0.61 | BRD4 (0.55) | MEN1KMT2ABRD4RETEGFR | |
| SCHEMBL14906434 | 0.61 | MEN1 (0.47) | MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |