Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146124 | 0.89 | KDM4E (0.44) | KDM4EGRNSORT1MAPK14RAB9A | |
| SCHEMBL352561 | 0.73 | KDM4E (0.37) | KDM4EGRNSORT1RAB9ANPC1 | |
| SCHEMBL10147474 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13618716 | 0.69 | KDM4E (0.40) | KDM4EGRNSORT1MAPK14LMNA | |
| SCHEMBL13618724 | 0.69 | GRN (0.40) | KDM4EGRNSORT1HDAC6 | |
| SCHEMBL21719732 | 0.67 | KDM4E (0.50) | KDM4EGRNSORT1MAPK14LMNA | |
| SCHEMBL13618719 | 0.66 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL13618555 | 0.65 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL13618717 | 0.65 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL13618548 | 0.65 | KDM4E (0.36) | KDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |