Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891703 | 0.80 | CPB1 (0.60) | L3MBTL3L3MBTL1TP53BP1ALOX5APFEN1 | |
| SCHEMBL13618525 | 0.79 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL8804588 | 0.78 | HTT (0.47) | L3MBTL3L3MBTL1TP53BP1ALOX5APFEN1 | |
| SCHEMBL24696444 | 0.77 | CYP2C19 (0.50) | L3MBTL3L3MBTL1TP53BP1RAB9AALDH1A1 | |
| SCHEMBL22551122 | 0.76 | HTT (0.55) | L3MBTL3L3MBTL1TP53BP1ALDH1A1TSHR | |
| SCHEMBL5871923 | 0.74 | ACHE (0.62) | L3MBTL3L3MBTL1PDK2RAB9AGRM5 | |
| SCHEMBL12442621 | 0.74 | ACHE (0.62) | L3MBTL3L3MBTL1PDK2RAB9AGRM5 | |
| SCHEMBL2720515 | 0.74 | ACHE (0.62) | L3MBTL3L3MBTL1PDK2RAB9AGRM5 | |
| SCHEMBL23133295 | 0.74 | HTT (0.62) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL31350912 | 0.74 | ALDH1A1 (0.58) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140467-A1 | OXOBENZINDOLIZINOQUINOLINES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2009-11-19 | — | — | WO | disclosed |