Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.47 |
| ▸ | PPARA | Q07869 | 19/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343050 | 0.89 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL1343316 | 0.81 | AURKA (0.44) | PPARGPPARA | |
| SCHEMBL1342248 | 0.78 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL4405822 | 0.78 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL1343918 | 0.78 | PPARA (0.60) | PPARGPPARA | |
| SCHEMBL4942052 | 0.77 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL1340732 | 0.76 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL4874812 | 0.75 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4874817 | 0.75 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4874822 | 0.75 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286776-A1 | HEXENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THEREOF | ZEILLER JEAN JACQUES | 2009-11-19 | — | — | US | disclosed |
| US-20090286776-A1 | HEXENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THEREOF | ZEILLER JEAN JACQUES | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286776-A1 | HEXENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THEREOF | GPR119, LIPA, ALOX5 | PPARG 95/4885PPARA 81/4885SMN1; SMN2 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.