Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057408 | 0.80 | TAAR1 (0.37) | TAAR1 | |
| SCHEMBL3871871 | 0.80 | TAAR1 (0.37) | TAAR1 | |
| SCHEMBL8217001 | 0.79 | GABRA1 (0.34) | TAAR1 | |
| SCHEMBL6464715 | 0.75 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL4177132 | 0.70 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL29506108 | 0.68 | — | — | |
| SCHEMBL560812 | 0.68 | — | — | |
| SCHEMBL338177 | 0.67 | GABRA1 (0.38) | — | |
| SCHEMBL19657170 | 0.67 | GABRA1 (0.41) | TAAR1 | |
| SCHEMBL29581892 | 0.67 | GABRA1 (0.41) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848694-B1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | HOFFMANN LA ROCHE (CH) | 2009-11-25 | — | — | EP | disclosed |