Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317964 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2AMAPTCYP3A4TDP1 | |
| SCHEMBL28389774 | 0.78 | MAPT (0.58) | MEN1KMT2AMAPTCYP3A4AHR | |
| Phosphoric Acid SCHEMBL22235321 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL13915153 | 0.78 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL22235320 | 0.77 | MEN1 (0.51) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL26480243 | 0.77 | MEN1 (0.49) | MEN1KMT2AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL14015372 | 0.74 | SLC22A6 (0.55) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL3227189 | 0.74 | LMNA (0.60) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL10689820 | 0.74 | MAPT (0.63) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL887095 | 0.74 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |