Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584691 | 0.91 | DRD2 (0.40) | DRD2DRD4CXCR6NPY5RFAAH | |
| SCHEMBL987416 | 0.91 | NPY5R (0.41) | DRD2DRD4NPY5RFAAHNPC1 | |
| SCHEMBL28795038 | 0.91 | NPY5R (0.41) | DRD2DRD4NPY5RFAAHNPC1 | |
| SCHEMBL2031203 | 0.86 | CXCR6 (0.36) | DRD2DRD4CXCR6NPY5RFAAH | |
| SCHEMBL12948849 | 0.84 | RAB9A (0.44) | DRD2DRD4HTR4HCRTR1HCRTR2 | |
| SCHEMBL12584224 | 0.82 | DRD2 (0.44) | DRD2DRD4FAAHHTR4HDAC3 | |
| SCHEMBL12584296 | 0.81 | MEN1 (0.43) | DRD2DRD4NPY5RHTR4CNR2 | |
| SCHEMBL12583874 | 0.81 | MEN1 (0.43) | DRD2DRD4NPY5RHTR4CNR2 | |
| SCHEMBL12584417 | 0.81 | DRD2 (0.41) | DRD2DRD4HTR4CNR2NPC1 | |
| SCHEMBL12584324 | 0.79 | KLK1 (0.49) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |