Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184542 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL11916218 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL12018602 | 0.84 | HTR3E (0.35) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL11919189 | 0.82 | HTR2A (0.37) | ALDH1A1HTTTSHRHSD17B10KMT2A | |
| SCHEMBL15600809 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL11916172 | 0.81 | LMNA (0.35) | ALDH1A1CYP3A4KMT2A | |
| SCHEMBL15217774 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL11900225 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL22232917 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HTTTDP1TSHR | |
| SCHEMBL15217772 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143389-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |