Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767958 | 0.92 | KMT2A (0.48) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL2258395 | 0.91 | LMNA (0.47) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL29202441 | 0.91 | LMNA (0.47) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL18114457 | 0.91 | LMNA (0.47) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL29144119 | 0.88 | CNR2 (0.46) | LMNAMMP12KMT2ACNR2 | |
| SCHEMBL29046858 | 0.85 | CPA1 (0.47) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL29046856 | 0.85 | CPA1 (0.47) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL28360416 | 0.84 | ERAP1 (0.50) | LMNAANPEPERAP1ERAP2KMT2A | |
| Cyclohexene SCHEMBL8776821 | 0.82 | FKBP1A (0.40) | LMNAMMP12ANPEPERAP1ERAP2 | |
| SCHEMBL10392265 | 0.82 | KMT2A (0.51) | LMNAANPEPERAP1ERAP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137691-A2 | 1,3-DIOL SYNTHESIS VIA CONTROLLED, RADICAL-MEDIATED C-H FUNCTIONALIZATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-11-12 | — | — | WO | disclosed |