SCHEMBL13619417

SCHEMBL13619417

O=C(CCCCCCC(F)(F)F)NO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 11/20 0.65
HDAC8 Q9BY41 10/20 0.65
HDAC6 Q9UBN7 7/20 0.65
HDAC3 O15379 6/20 0.65
HDAC2 Q92769 6/20 0.65
HDAC5 Q9UQL6 3/20 0.65
HSP90AA1 P07900 1/20 0.54
HDAC11 Q96DB2 4/20 0.44
HDAC10 Q969S8 3/20 0.44
NCOR2 Q9Y618 3/20 0.44
HDAC4 P56524 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
ALOX5 P09917 1/20 0.43
KDM4E B2RXH2 1/20 0.43
BRD4 O60885 1/20 0.43
NCOR1 O75376 1/20 0.43
NR1I2 O75469 1/20 0.43
EGFR P00533 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azelaic Bis Hydroxamic Acid SCHEMBL4741072 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL11767258 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL11764904 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
Suberohydroxamic Acid SCHEMBL2159033 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL10439098 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL11769965 0.81 HDAC1 (1.00) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL8977839 0.78 HDAC8 (0.65) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL8977834 0.78 HDAC8 (0.65) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL11768749 0.78 HDAC1 (0.93) HDAC1HDAC8HDAC6HDAC3HDAC2
SCHEMBL11508310 0.77 HAO1 (0.38) HDAC1HDAC8HDAC6HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618682-B2 Method for providing an anti-stiction coating on a metal surface HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-11-17 US disclosed
US-20080074771-A1 Method for providing an anti-stiction coating on a metal surface HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-03-27 US disclosed