Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 3/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948788 | 0.92 | PTGER4 (0.48) | PTGER4ACACBPHGDHPTGDRPTGER2 | |
| SCHEMBL12585296 | 0.89 | PHGDH (0.56) | PTGER4PHGDHPTGDRPTGER2 | |
| SCHEMBL12584531 | 0.88 | CYP1A2 (0.47) | PTGER4PHGDHPTGDRGPR139TP53 | |
| SCHEMBL10085708 | 0.85 | PTGER4 (0.48) | PTGER4ACACBPHGDHPTGDRPTGER2 | |
| SCHEMBL12583919 | 0.84 | P2RX3 (0.42) | ALDH1A1LMNAP2RX3 | |
| SCHEMBL12584692 | 0.81 | RAB9A (0.58) | PTGER4ACACBPHGDHPTGER2P2RX3 | |
| SCHEMBL12585324 | 0.81 | PHGDH (0.54) | PTGER4PHGDHPTGDRPTGER2 | |
| SCHEMBL12948790 | 0.81 | P2RX3 (0.46) | PTGER4ACACBPHGDHPTGDRPTGER2 | |
| SCHEMBL12584141 | 0.79 | PTGER4 (0.48) | PTGER4PTGDRGPR139TP53P2RX3 | |
| SCHEMBL13619447 | 0.79 | MAPT (0.68) | TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |