Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851624 | 0.80 | CTBP2 (0.42) | SIGMAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30028149 | 0.78 | ALDH1A1 (0.45) | SIGMAR1CES1L3MBTL1TDP1MEN1 | |
| SCHEMBL31621835 | 0.74 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL27704682 | 0.74 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL17311800 | 0.72 | EPHX2 (0.50) | SIGMAR1EPHX2MEN1KMT2AHDAC8 | |
| SCHEMBL1535652 | 0.71 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL12670826 | 0.71 | HTR2C (0.45) | SIGMAR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL10204064 | 0.71 | CES2 (0.50) | CES1CES2AKR1B1L3MBTL1TDP1 | |
| SCHEMBL17948490 | 0.70 | CES1 (0.41) | CES1CES2AKR1B1L3MBTL1TDP1 | |
| SCHEMBL19882763 | 0.69 | CES2 (0.42) | CES1CES2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142314-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2009-11-26 | — | — | WO | disclosed |