SCHEMBL13619827

SCHEMBL13619827

O=C(O)c1c(O)n2ccccc2c(CC2C=COC2)c1=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13620403 0.67 BAZ2B (0.41) IDO1PTGS2
SCHEMBL1127325 0.67 IDO1 (0.35) IDO1PTGS2
SCHEMBL13620039 0.67 ERCC5 (0.46)
SCHEMBL371112 0.58 IDO1 (0.51) IDO1PTGS2
SCHEMBL13658262 0.56 ALDH1A1 (0.54) IDO1
SCHEMBL11266949 0.56 IDO1 (0.49) IDO1PTGS2
SCHEMBL28793633 0.54 IDO1 (0.50) IDO1PTGS2
SCHEMBL474021 0.54 FNTA (0.53) IDO1PTGS2
SCHEMBL10797022 0.54 IDO1 (0.40) IDO1PTGS2
SCHEMBL5242920 0.53 IDO1 (0.46) IDO1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009134616-A2 NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION INTERMUNE, INC. (US) 2009-11-05 WO disclosed