Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127411 | 0.86 | ALDH1A1 (0.43) | BAZ2BBAZ2AALDH1A1KDM4EGFER | |
| SCHEMBL13620039 | 0.84 | ERCC5 (0.46) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL1127325 | 0.80 | IDO1 (0.35) | BAZ2BBAZ2AIDO1PTGS2 | |
| SCHEMBL1127254 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL1127987 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4ECCR6HKDC1CYP3A4 | |
| SCHEMBL1127428 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL1128142 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4EG6PDCYP3A4MAPK1 | |
| SCHEMBL4289628 | 0.68 | KDM4E (0.44) | ALDH1A1KDM4EG6PDCYP3A4MAPK1 | |
| SCHEMBL13658303 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EG6PDCYP3A4MAPK1 | |
| SCHEMBL13619827 | 0.67 | IDO1 (0.34) | IDO1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |